The route connects the city of DeQuincy with US 171 and US 190, two of the region's main highways. LA 12 traverses an area of the state known as Acadiana and is also signed as the Acadiana Trail.
It runs 34.64 miles (55.75 km) in an east–west direction from the Texas state line west of Starks to a junction with U.S.
Louisiana Highway 12 ( LA 12) is a state highway located in southwestern Louisiana.